A case with acute-on-chronic liver failure receiving liver transplantation during daclatasvir and asunaprevir therapy in chronic hepatitis C patient
نویسندگان
چکیده
منابع مشابه
Acute on Chronic Liver Failure Due to Acute Hepatitis C
Acute-on-chronic liver failure develops in a setting of acute decompensation of chronic liver disease, associated with organ failure and high mortality rate. Many causes have been described as the “trigger event”. Viral hepatitis A, B and E is considered precipitating events and several studies have addressed this issue. Acute hepatitis C has been described as a cause of acute liver failure but...
متن کاملOutcomes of treatment with daclatasvir and asunaprevir for recurrent hepatitis C after liver transplantation.
AIM The development of direct-acting oral agents has dramatically changed the treatment strategy of hepatitis C virus (HCV) infection. Here we aimed to reveal the efficacy and safety of daclatasvir (DCV) and asunaprevir (ASV) for recurrent HCV genotype 1 infection after liver transplantation (LT). METHODS A retrospective study was undertaken on nine patients who underwent a 24-week DCV/ASV tr...
متن کاملAsunaprevir/daclatasvir and sofosbuvir/ledipasvir for recurrent hepatitis C following living donor liver transplantation.
AIM This study aimed to clarify the efficacy and safety of interferon-free therapy using asunaprevir and daclatasvir, or sofosbuvir and ledipasvir for post living donor liver transplantation (LDLT) recipients with hepatitis C virus (HCV). METHODS A retrospective cohort study of LDLT recipients with HCV genotype 1b treated with asunaprevir (100 mg twice daily) and daclatasvir (60 mg once daily...
متن کامل[Acute on chronic liver failure].
Acute-on-Chronic Liver Failure (ACLF) is a recently introduced term defined as severe acute deterioration of an established liver disease. This entity usually develops after an acute insult. The main clinical manifestations are hepatorenal syndrome, hepatic encephalopathy and organ failure, with a high risk of death in the short term. The true incidence of ACLF remains difficult to determine du...
متن کاملAcute-on-chronic liver failure.
Acute-on-chronic liver failure combines an acute deterioration in liver function in an individual with pre-existing chronic liver disease and hepatic and extrahepatic organ failures, and is associated with substantial short-term mortality. Common precipitants include bacterial and viral infections, alcoholic hepatitis, and surgery, but in more than 40% of patients, no precipitating event is ide...
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ژورنال
عنوان ژورنال: Gastroenterology Report
سال: 2018
ISSN: 2052-0034
DOI: 10.1093/gastro/goy012